The Effectiveness of α-Mangostin in Reducing the Streptococcus Mutans Biofilm Thickness

Dental caries occurs due to the demineralization of tooth structure caused by microorganisms in colonies called biofilms. One involved dental is Streptococcus mutans. Oral mouthwash, addition mechanical cleaning, known prevent growth oral microorganisms. Mangosteen as an anti-cancer ingredient with high anti-bacterial properties. This study aims identify effectiveness mangosteen skin extract (Garcinia mangostana L.) decreasing mutans biofilm. The experimental research a post-test control group design. sample was divided into five groups; 3 treatment groups and 2 groups. biofilm thickness test carried out OD (Optical density) wavelength about 620 nm using ELISA reader. Kruskal Wallis analysis employed non-parametric statistical analysis. Statistical indicated significant differences 5 lowest average yield α-mangosteen at 12.5 g/ml. Conclusion: effectively reduced